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Suppliers for CAS
1088965-37-0
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Properties | CAS |
1088965-37-0 | Formula |
C32H38ClN5O4 |
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3 Registered suppliers
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C32H38ClN5O4 Molecular Weight: 592.12822
Aea.ltd
P.R.China
Molecular Formula: C32H38ClN5O4 Molecular Weight: 592.12822
BOC Sciences
USA
Description : GSK-923295 is a novel antimitotic inhibitor of centromere-associated protein E (CENP-E) with potential anticancer activity. GSK-923295 demonstrated significant antitumor activity against solid tumor models, inducing CRs in Ewing sarcoma, rhabdoid, and rhabdomyosarcoma xenografts. Clinical study showed that GSK-923295 had dose-proportional pharmacokinetics and a low number of grade 3 or 4 adverse events. The observed incidence of myelosuppression and neuropathy was low. Further investigations may provide a more complete understanding of the potential for GSK-923295 as an antiproliferative agent. - Molecular Weight :592.14
- Purity :98%
Molecular Formula : C32H38ClN5O4 Canonical SMILES : CC(C)OC1=C(C=C(C=C1)C(=O)NC(CC2=CC=C(C=C2)C3=CN4C=CC=C(C4=N3)C(C)O)CNC(=O)CN(C)C)Cl InChI : InChI=1S/C32H38ClN5O4/c1-20(2)42-29-13-12-24(16-27(29)33)32(41)35-25(17-34-30(40)19-37(4)5)15-22-8-10-23(11-9-22)28-18-38-14-6-7-26(21(3)39)31(38)36-28/h6-14,16,18,20-21,25,39H,15,17,19H2,1-5H3,(H,34,40)(H,35,41)/t21-,25-/m0/s1 InChIKey : WHMXDBPHBVLYRC-OFVILXPXSA-N Appearance : Light Yellow Powder Storage : - 20 °C Synonyms : GSK923295; GSK 923295; GSK-923295; GSK-923295A; GSK923295A; GSK 923295A
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Last update 2024-06-30
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