Description:
NVS-PAK1-1 is potent and specific allosteric PAK1 inhibitor (IC50 = 5 nM) with selective over PAK2 and a panel of 442 kinases.
- Molecular Weight: 479.93
- Molecular Formula: C23H25ClF3N5O
Canonical SMILES:
CC(C)NC(=O)N1CCC(C1)NC2=NC3=C(C=CC(=C3)F)N(C4=C2C=C(C=C4)Cl)CC(F)F
InChI:
1S/C23H25ClF3N5O/c1-13(2)28-23(33)31-8-7-16(11-31)29-22-17-9-14(24)3-5-19(17)32(12-21(26)27)20-6-4-15(25)10-18(20)30-22/h3-6,9-10,13,16,21H,7-8,11-12H2,1-2H3,(H,28,33)(H,29,30)/t16-/m0/s1
InChIKey: OINGHOPGNMYCAB-INIZCTEOSA-N- Boiling Point: 697.8±55.0 °C at 760 Torr
- Solubility: DMSO: ≥125 mg/mL
- Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
NVS-PAK1-1; NVSPAK11; NVS PAK1 1; (3S)-3-[[8-chloro-11-(2,2-difluoroethyl)-3-fluorobenzo[b][1,4]benzodiazepin-6-yl]amino]-N-propan-2-ylpyrrolidine-1-carboxamide
More details are to be found on supplier website
