Description:
TDZD-8 is a derivative of thiadiazolidine (TDZD) and acts as a non-ATP competitive inhibitor of GSK3β. It was shown to inhibit proliferation and self-renewal of glioblastoma stem cells.
- Molecular Weight: 222.262
- Molecular Formula: C10H10N2O2S
Purity: >98%
Canonical SMILES:
CN1C(=O)N(C(=O)S1)CC2=CC=CC=C2
InChI:
InChI=1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3
InChIKey: JDSJDASOXWCHPN-UHFFFAOYSA-N
- Melting Point: 60-61°C
- Appearance: White Solid
Synonyms:
4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione; GSK-3beta Inhibitor I; TDZD 8; 1,2,4-Thiadiazolidine-3,5-dione, 2-methyl-4-(phenylmethyl)-
More details are to be found on supplier website