Description:
Geclosporin is an impurity of cycloporine, which is an immunosuppressant used in the treatment of rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, etc.
- Molecular Weight: 1.216.662
- Molecular Formula: C63H113N11O12
Purity: ≥90% by HPLC
Canonical SMILES:
CCCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
InChI:
InChI=1S/C63H113N11O12/c1-25-27-29-41(15)53(76)52-57(80)66-44(28-26-2)59(82)68(18)34-49(75)69(19)45(30-35(3)4)56(79)67-50(39(11)12)62(85)70(20)46(31-36(5)6)55(78)64-42(16)54(77)65-43(17)58(81)71(21)47(32-37(7)8)60(83)72(22)48(33-38(9)10)61(84)73(23)51(40(13)14)63(86)74(52)24/h25,27,35-48,50-53,76H,26,28-34H2,1-24H3,(H,64,78)(H,65,77)(H,66,80)(H,67,79)/b27-25+/t41-,42+,43-,44+,45+,46+,47+,48+,50+,51+,52+,53-/m1/s1
InChIKey: ZMKGDQSIRSGUDJ-VSROPUKISA-N
- Boiling Point: 1297.8±65.0 °C(Predicted)
- Melting Point: 182-187°C
- Solubility: Soluble in Chloroform, Methanol
- Appearance: White to Off-white Solid
- Application: immunosuppressant
- Storage: Store at -20°C
Synonyms:
Cyclosporin G; Cyclosporine G
More details are to be found on supplier website
