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Suppliers for CAS
1454846-35-5
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Properties | | CAS |
1454846-35-5 | | Formula |
C21H19FN6O2 |
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9 Registered suppliers
Amadis Chemical Company Limited
P.R.China
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
Capot Chemical Co., Ltd.
P.R.China
More details are to be found here
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C21H19FN6O2
Molecular Weight: 406.4129632
Shandong Ench Chemical Co.,Ltd
P.R.China
Assay : 99% min
Appearance : white powder
The third-generation ALK inhibitor can inhibit 9 mutations that are resistant to crizotinib, has a strong blood-brain barrier permeability, and has a strong brain effect.
It is especially suitable for patients with advanced NSCLC who are resistant to other ALKs.
Aea.ltd
P.R.China
Assay : 99% min
Appearance : white powder
The third-generation ALK inhibitor can inhibit 9 mutations that are resistant to crizotinib, has a strong blood-brain barrier permeability, and has a strong brain effect.
It is especially suitable for patients with advanced NSCLC who are resistant to other ALKs.
Assay : 99% min
Appearance : white powder
The third-generation ALK inhibitor can inhibit 9 mutations that are resistant to crizotinib, has a strong blood-brain barrier permeability, and has a strong brain effect.
It is especially suitable for patients with advanced NSCLC who are resistant to other ALKs.
Hangzhou Lingrui Chemical Co., Ltd.
P.R.China
Assay : 99% min
Appearance : white powder
The third-generation ALK inhibitor can inhibit 9 mutations that are resistant to crizotinib, has a strong blood-brain barrier permeability, and has a strong brain effect.
It is especially suitable for patients with advanced NSCLC who are resistant to other ALKs.
BOC Sciences
USA
Description : Lorlatinib is an ATP-competitive ROS1/ALK inhibitor with potential antitumor activity. Lorlatinib binds to both ALK and ROS1 kinases, resulting in disruption of ALK- and ROS1-mediated signaling and inhibition of ALK- and ROS1-overexpressing tumor cells. - Molecular Weight :406.421
- Boiling Point :675.0±55.0 °C at 760 mmHg
- Melting Point :184-187°C
- Purity :≥98%
Molecular Formula : C21H19FN6O2 Canonical SMILES : CC1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C
InChI :
InChI=1S/C21H19FN6O2/c1-11-15-7-13(22)4-5-14(15)21(29)27(2)10-16-19(17(8-23)28(3)26-16)12-6-18(30-11)20(24)25-9-12/h4-7,9,11H,10H2,1-3H3,(H2,24,25)/t11-/m1/s1
InChIKey :
IIXWYSCJSQVBQM-LLVKDONJSA-N
Appearance :
White Solid
Synonyms :
PF06463922; PF 06463922; PF-06463922; PF-6463922; PF6463922; PF 6463922; Loratinib.
More details are to be found here
Autech Industry Co.,Limited
P.R.China
Description : Lorlatinib is an ATP-competitive ROS1/ALK inhibitor with potential antitumor activity. Lorlatinib binds to both ALK and ROS1 kinases, resulting in disruption of ALK- and ROS1-mediated signaling and inhibition of ALK- and ROS1-overexpressing tumor cells. - Molecular Weight :406.421
- Boiling Point :675.0±55.0 °C at 760 mmHg
- Melting Point :184-187°C
- Purity :≥98%
Molecular Formula : C21H19FN6O2 Canonical SMILES : CC1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C
InChI :
InChI=1S/C21H19FN6O2/c1-11-15-7-13(22)4-5-14(15)21(29)27(2)10-16-19(17(8-23)28(3)26-16)12-6-18(30-11)20(24)25-9-12/h4-7,9,11H,10H2,1-3H3,(H2,24,25)/t11-/m1/s1
InChIKey :
IIXWYSCJSQVBQM-LLVKDONJSA-N
Appearance :
White Solid
Synonyms :
PF06463922; PF 06463922; PF-06463922; PF-6463922; PF6463922; PF 6463922; Loratinib.
More details are to be found here
Detailed information on the suppliers of
Lorlatinib |
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