BGC > Product Search > XL-647

Molecular Formula: C24H25Cl2FN4O2
Molecular Weight: 491.3853032

Description :
XL647 is an orally bioavailable small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity. It inhibits EGFR, HER2, VEGFR and EphB4 kinase.

• Molecular Weight :491.39
• Purity :> 98%

Molecular Formula :
C24H25Cl2FN4O2
Canonical SMILES :
CN1CC2CC(CC2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC
InChI :
InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13?,14-,15+
InChIKey :
HVXKQKFEHMGHSL-GOOCMWNKSA-N
Synonyms :
XL-647; XL 647; XL647; EXEL-7647; EXEL 7647; EXEL7647; KD-019; KD 019; KD019

More details are to be found here

Description :
XL647 is an orally bioavailable small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity. It inhibits EGFR, HER2, VEGFR and EphB4 kinase.

• Molecular Weight :491.39
• Purity :> 98%

Molecular Formula :
C24H25Cl2FN4O2
Canonical SMILES :
CN1CC2CC(CC2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC
InChI :
InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13?,14-,15+
InChIKey :
HVXKQKFEHMGHSL-GOOCMWNKSA-N
Synonyms :
XL-647; XL 647; XL647; EXEL-7647; EXEL 7647; EXEL7647; KD-019; KD 019; KD019

More details are to be found here