BGC > Product Search > tert-Butyloxycarbonyl-valyl-citrullyl-(4-aminobenzyl)-(4-nitrophenyl)carbonate | 870487-10-8

Molecular Formula: C30H40N6O10
Molecular Weight: 644.6728

Description :
Boc-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell.

• Molecular Weight :644.7
• Purity :95%

Molecular Formula :
C30H40N6O10
Canonical SMILES :
CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)COC(=O)OC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)OC(C)(C)C
InChI :
InChI=1S/C30H40N6O10/c1-18(2)24(35-28(40)46-30(3,4)5)26(38)34-23(7-6-16-32-27(31)39)25(37)33-20-10-8-19(9-11-20)17-44-29(41)45-22-14-12-21(13-15-22)36(42)43/h8-15,18,23-24H,6-7,16-17H2,1-5H3,(H,33,37)(H,34,38)(H,35,40)(H3,31,32,39)/t23-,24-/m0/s1
InChIKey :
SKWLDDHVHXQPOG-ZEQRLZLVSA-N
Storage : -20°C
Synonyms :
EX-A4143

More details are to be found here

Formula:
C30H40N6O10
Mol Weight:
644,67g/mol
Synonym:
t-butyl (S)-3-methyl-1-((S)-1-(4-(((4-nitrophenoxy)carbonyloxy)methyl)phenylamino)-1-oxo-5-ureidopentan-2-ylamino)-1-oxobutan-2-ylcarbamate

More details are to be found here

Description: ADC-Linker
Molecular formula: C30H40N6O10