BGC > Product Search > LSD1-IN-1 | 1431326-61-2

Molecular Formula: C15H24Cl2N2
Molecular Weight: 303.27046

Molecular Formula: C15H24Cl2N2
Molecular Weight: 303.27046

Molecular Formula: C15H24Cl2N2
Molecular Weight: 303.27046

Description :
ORY-1001 is a lysine specific demethylase 1 inhibitor under the development of Oryzon with IC50 value < 20nM. It selectively inhibits related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B > 100uM, SMOX 7uM). ORY-1001 can induce apoptosis in THP-1 and inhibit proliferation and colony formation of MV(4;11) (MLL-AF4) cells (EC50 <1nM). In THP-1 (MLL-AF9) cells, ORY-1001 results in a time-dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers.

• Molecular Weight :303.27
• Purity :> 98%

Molecular Formula :
C15H24Cl2N2
Canonical SMILES :
C1CC(CCC1N)NC2CC2C3=CC=CC=C3.Cl.Cl
InChI :
InChI=1S/C15H22N2.2ClH/c16-12-6-8-13(9-7-12)17-15-10-14(15)11-4-2-1-3-5-11;;/h1-5,12-15,17H,6-10,16H2;2*1H/t12?,13?,14-,15+;;/m0../s1
InChIKey :
UCINOBZMLCREGM-RNNUGBGQSA-N
Solubility :
Soluble in DMSO.
Appearance :
Solid Powder
Storage : Store at -20 °C
Synonyms :
RG-6016; RG 6016; RG6016; ORY-1001 2HCl; ORY 1001 2HCl; ORY1001 2HCl; (1R,4R)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride

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