BGC > Produktsuche > Niraparib tosylate | 1038915-73-9

Molecular Formula: C26H28N4O4S
Molecular Weight: 492.58992

Molecular Formula: C26H30N4O5S
Molecular Weight: 510.6052

Description:
MK-4827 tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. It has a great activity in cancer cells with mutant BRCA-1 and BRCA-2, >330-fold selective against PARP3, V-PARP and Tank1.

• Molecular Weight:492.59
• Purity:>98%

Molecular Formula:
C26H28N4O4S
Canonical SMILES:
O=C(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C12)N.O=S(C5=CC=C(C)C=C5)(O)=O
InChI:
1S/C19H20N4O.C7H8O3S/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14;1-6-2-4-7(5-3-6)11(8,9)10/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24);2-5H,1H3,(H,8,9,10)/t14-;/m1./s1
InChIKey:
LCPFHXWLJMNKNC-PFEQFJNWSA-N
Appearance:
Light yellow solid powder
Synonyms:
(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulfonate; MK-4827; MK-4827; MK4827; MK4827-tosylate; Niraparib tosylate