Molecular Weight: 417.81
Molecular Formula: C20H15ClF3N5
Canonical SMILES: FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F
Purity: 98%
Solubility: Soluble in DMSO, not in water
Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Synonyms: PLX3397; PLX-3397; PLX 3397; Pexidartinib
DescriptionPexidartinib (PLX3397) is an oral, potent mutil-targeted receptor tyrosine kinase inhibitor of CSF-1R with IC50 of 20 nM, Kit with IC50 of 10 nM, and Flt3 with IC50 160 nM. Phase 3, respectively.
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