Molecular Weight: 279.19
Molecular Formula: C8H14N3O6P
Canonical SMILES: C1=CN(C(=O)N=C1N)CC(CO)OCP(=O)(O)O
InChI: InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1
InChIKey: VWFCHDSQECPREK-LURJTMIESA-N
Boiling Point: 609.5±65.0°C (Predicted)
Melting Point: 260°C (dec.)
Purity: ≥98% by HPLC
Solubility: Soluble in Deionized Water (≥5 mg/mL, Warmed)
Storage: Store at -20°C
Synonyms: Vistide; HPMPC; (S)-HPMPC; Cidofovir anhydrous; GS-504; GS 504; GS504; (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine; (S)-(((1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid
DescriptionCidofovir is inhibitory to CMV plaque formation even when added to the cells at 48 hr post infection with IC50 of 0.9 μg/mL for Davis and 1.6 μg/mL for AD-169 strains,respectively.
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