Molecular Weight: 294.31
Molecular Formula: C17H14N2O3
Canonical SMILES: C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
InChI: InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
InChIKey: TUCIOBMMDDOEMM-RIYZIHGNSA-N
Purity: 0.98
Application: Antineoplastic Agents
Synonyms: Tyrphostin AG 490; AG-490; AG490
DescriptionTyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells.
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