CAS No. 1443246-62-5

Molecular Formula: C17H14F2N4O
Hazard Symbols: N
UN Number: UN 3077 9 / PGIII
WGKGermany: 3

Molecular Weight: 328.32
Molecular Formula: C17H14F2N4O
Canonical SMILES: CC1=NN(C(=C1)NC(=O)NC2=CC(=C(C=C2)F)F)C3=CC=CC=C3
InChI: InChI=1S/C17H14F2N4O/c1-11-9-16(23(22-11)13-5-3-2-4-6-13)21-17(24)20-12-7-8-14(18)15(19)10-12/h2-10H,1H3,(H2,20,21,24)
InChIKey: IEKSMUSSYJUQMY-UHFFFAOYSA-N
Boiling Point: 377.8±42.0 °C at 760 mmHg
Purity: ≥99% by HPLC
Synonyms: ML297; ML 297; ML-297; N-(3,4-Difluorophenyl)-N'-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea
Description
ML 297 is a Kir3.1/3.2 (GIRK1/2) channel activator with IC50 values of 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3.


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