CAS No. 1469924-27-3

Molecular Formula: C17H21N3O
Molecular Weight: 283.36814
Hazard Symbols: Xn

Molecular Weight: 283.37
Molecular Formula: C17H21N3O
Canonical SMILES: CN(C)C1=CC=C(C=C1)C2=CC(=CC=C2)NC(=O)N(C)C
InChI: InChI=1S/C17H21N3O/c1-19(2)16-10-8-13(9-11-16)14-6-5-7-15(12-14)18-17(21)20(3)4/h5-12H,1-4H3,(H,18,21)
InChIKey: AWOPBSAJHCUSAS-UHFFFAOYSA-N
Purity: 0.98
Synonyms: Atglistatin; 1469924-27-3; 3-(4'-(Dimethylamino)-[1,1'-biphenyl]-3-yl)-1,1-dimethylurea; CHEMBL3823931; MFCD28009494; 3-[3-[4-(dimethylamino)phenyl]phenyl]-1,1-dimethylurea; 3-[4'-(Dimethylamino)-biphenyl-3-yl]-1,1-dimethylurea; 3-(4'-(dimethylamino)biphenyl-3-yl)-1,1-dimethylurea; 1-[4'-(DIMETHYLAMINO)-[1,1'-BIPHENYL]-3-YL]-3,3-DIMETHYLUREA; SCHEMBL15186954; Atglistatin, >=98% (HPLC); GTPL12995; EX-A293; AWOPBSAJHCUSAS-UHFFFAOYSA-N; HMS3653A18; HMS3744A05; BCP27988; BDBM50185419; s7364; AKOS026750242; CCG-267281; compound 4 [PMID: 24096302]; NCGC00371133-07; NCGC00371133-10; AC-35213; AS-16730; HY-15859; SY038696; FT-0700208; SW220102-1; EN300-172737; A884474; SR-03000003442; J-690187; SR-03000003442-1; 2-[(N-Benzyl-L-phenylalanyl)amino]-5-iodobenzoic acid; Z1785637773; Urea, N'-[4'-(dimethylamino)[1,1'-biphenyl]-3-yl]-N,N-dimethyl-; 3-[4 inverted exclamation mark -(Dimethylamino)-biphenyl-3-yl]-1,1-dimethylurea
Description
Atglistatin is a highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL) with an IC50 of ~0.7 μM for inhibition of lipolysis in vitro, but no toxicity up to a concentration of 50 μM.


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