Molecular Weight: 300.05
Molecular Formula: Cl2H6N2Pt
Canonical SMILES: [Cl-][Pt+2]([Cl-])([NH3])[NH3]
InChI: InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
InChIKey: LXZZYRPGZAFOLE-UHFFFAOYSA-L
Melting Point: 270°C
Purity: >98%
Application: Antineoplastic agent
Storage: Store at RT
Synonyms: (SP-4-2)-diamminedichloro-platinum
DescriptionCisplatin induces cytotoxicity by interaction with DNA to form DNA adducts which activate several signal transduction pathways, including Erk, p53, p73, and MAPK, which culminates in the activation of apoptosis. It is used in several types of cancer.
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