CAS No. 187235-37-6

Molecular Formula: C14H12F3N3O5
Molecular Weight: 359.2573896

Molecular Weight: 359.26
Molecular Formula: C14H12F3N3O5
Canonical SMILES: C1C(COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F
InChI: InChI=1S/C14H12F3N3O5/c15-14(16,17)25-10-3-1-9(2-4-10)7-23-11-5-19-6-12(20(21)22)18-13(19)24-8-11/h1-4,6,11H,5,7-8H2/t11-/m0/s1
InChIKey: ZLHZLMOSPGACSZ-NSHDSACASA-N
Boiling Point: 462.3±55.0
Melting Point: >140°C
Purity: >98%
Solubility: <1 mg/mL
Synonyms: PA824; PA-824; PA 824; Pretomanid.
Description
PA-824, a bioreductive drug. PA-824 has potent in vitro activity against Mycobacterium tuberculosis. PA-824 was tested in vitro against a broad panel of multidrug-resistant clinical isolates and was found to be highly active against all isolates (MIC<1 microg/ml). PA-824 showed significant activity at 2, 10, and 50 microg/ml, similar to that of metronidazole, in a dose-dependent manner.


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Smile code:
FC(F)(F)OC1=CC=C(C=C1)CO[C@H]2CN3C(OC2)=NC([N+]([O-])=O)=C3
MDL Number:
MFCD06809939
Purity :
98%
Available in stock:
12.849 g