CAS No. 209783-80-2

Molecular Formula: C21H20N4O3
Molecular Weight: 376.4085
Hazard Symbols: Xi,T
UN Number: UN 2811 6.1 / PGIII
WGKGermany: 3
HS Code: 29333990

Molecular Weight: 376.416
Molecular Formula: C21H20N4O3
Canonical SMILES: C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
InChI: InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
InChIKey: INVTYAOGFAGBOE-UHFFFAOYSA-N
Melting Point: 154-156°C
Purity: > 98%
Application: Histone Deacetylase Inhibitors
Synonyms: MS275; MS-275; MS 2275; SNDX275; SNDX-275; SNDX 275; Entinostat; pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
Description
Entinostat is a histone deacetylase (HDAC) inhibitor displaying antiproliferative and antineoplastic effects. Entinostat induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), which slows cell growth, differentiation, and tumor development in vivo. Entinostat is potentially used as an antitumor drug in combination with other drugs like adriamycin, PARP inhibitors and Hsp90 inhibitors.


More details are to be found on supplier website

Smile code:
O=C(OCC1=CC=CN=C1)NCC2=CC=C(C(NC3=CC=CC=C3N)=O)C=C2
MDL Number:
MFCD08272435
Purity :
98%
Available in stock:
49.494 g