Molecular Weight: 230.26
Molecular Formula: C14H14O3
Canonical SMILES: CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O
InChI: InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
InChIKey: CMWTZPSULFXXJA-VIFPVBQESA-N
Boiling Point: 403.9°C at 760 mmHg
Melting Point: 153 °C
Purity: >98%
Solubility: Soluble in Water (15.9 mg/L)
Application: the treatment of rheumatoid arthritis and gout
Synonyms: (S)-6-Methoxy-α-methyl-2-naphthaleneacetic Acid; po-Naproxen; Aproxen; Bonyl; CG 3117; CG3117; CG-3117; Diocodal; Dysmenalgit; Equiproxen; Floginax; Laraflex; Laser; MNPA; Naixan; Napren; Naprium; Naprius; Naprosyn; Naprosyne; Naproxen; Naprux; Naxen; Nycopren; Panoxen; Prexan; Proxen; Proxine; RS 3540; RS3540; RS-3540; Reuxen; Veradol; Xenar; Xenar-CR; d-2-(6-Methoxy-2-naphthyl)propionic Acid; d-Naproxen
Description(S)-Naproxen is a non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively. It is an anti-inflammatory agent with analgesic and antipyretic activities, which is commonly used for the treatment of rheumatoid arthritis and gout.
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