CAS No. 292605-14-2

Molecular Formula: C15H14O3S2
Molecular Weight: 306.39986
Hazard Symbols: Xi
WGKGermany: 3
HS Code: 29349990

Molecular Weight: 306.394
Molecular Formula: C15H14O3S2
Canonical SMILES: C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3
InChI: InChI=1S/C15H14O3S2/c16-20(17,11-14-10-19-14)15-8-6-13(7-9-15)18-12-4-2-1-3-5-12/h1-9,14H,10-11H2
InChIKey: LSONWRHLFZYHIN-UHFFFAOYSA-N
Purity: 98%
Synonyms: MMP-2/MMP-9 Inhibitor IV; 2-((4-phenoxyphenylsulfonyl)methyl)thiirane; SB-3CT; SB3CT; SB3-CT; IN1250; IN 1250; IN-1250
Description
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. SB-3CT is a 2-[(arylsulfonyl)methyl]thiirane that achieves potent inhibition, by a thiirane-opening mechanism, of the MMP2 and MMP9 zinc metalloproteases. SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. Besides, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis.


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