CAS No. 363600-92-4

Molecular Weight: 285.30
Molecular Formula: C16H15NO4
Canonical SMILES: CC1=C(C=CC=C1N=CC2=C(C(=CC=C2)OC)O)C(=O)O
InChI: InChI=1S/C16H15NO4/c1-10-12(16(19)20)6-4-7-13(10)17-9-11-5-3-8-14(21-2)15(11)18/h3-9,18H,1-2H3,(H,19,20)
InChIKey: WTGMGRFVBFDHGQ-UHFFFAOYSA-N
Boiling Point: 505.7±50.0 °C at 760 Torr
Solubility: DMSO: ≥ 30 mg/mL
Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms: TLR2-IN-C29; TLR2 IN C29; TLR2INC29; TLR2-inhibitor-C29; TLR2 inhibitor-C29; TLR2 inhibitor C29
Description
C29 is a potential TLR2 inhibitor. C29 inhibited TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.


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