Molecular Weight: 230.7
Molecular Formula: C8H7ClN2O2S
Canonical SMILES: CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
InChI: InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
InChIKey: GDLBFKVLRPITMI-UHFFFAOYSA-N
Melting Point: 330-331 °C.
Purity: 98% (TLC).
Solubility: In methanol, slightly in dilute aqueous base, insoluble in water
Application: Antihypertensive Agents
Storage: Store at room temperature.
Synonyms: 7-Chloro-3-methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide
DescriptionDiazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular release of potassium switches off voltage-gated calcium ion channels which inhibits the generation of an action potential.
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