CAS No. 41100-52-1

Properties	white crystalline powder.
melting point	290-295deg C.
Specification	≥ 98.5%(GC)

Molecular Formula: C12H21N.HCl
Molecular Weight: 215,77


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Molecular Weight: 215.76
Molecular Formula: C12H21N.HCl
Canonical SMILES: CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl
InChI: InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H
InChIKey: LDDHMLJTFXJGPI-UHFFFAOYSA-N
Melting Point: >300°C (sublimes)
Purity: >98%
Solubility: 29.4 [ug/mL] (The mean of the results at pH 7.4)
Application: Antiparkinson Agents
Synonyms: 3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-amine Hydrochloride; 3,5-Dimethyl-1- adamantanamine; 1-Amino-3,5-dimethyladamantane Hydrochloride; Akatinol; Axura; Ebix; Ebixia; Ebixza; NSC 102290; Namenda; SUN Y7017; Tocris
Description
Memantine is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA receptors.It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively.


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Appearance
white or almost white crystalline
powder
Conform
Identification (1), (2)conform Conform
Water ≤1.0% 0.41%
Heavy metals ＜0.002% Conform
Residue on ignition ≤0.1% 0.06%
Related others
Individual impurity ＜0.5% 0.23%
Total impurity ＜1.0% 0.45%
Total chlorides 16.2~16.7% 16.5%
Assay ≥99.0% 99.38%
Particle size ≤100um Conform