CAS No. 540737-29-9

Molecular Formula: C16H20N6O.C6H8O7
Molecular Weight: 504.497
WGKGermany: 3
HS Code: 29335990

Purity: 98% min
Application: Tofacitinib is indicated for moderate-to-severe rheumatoid arthritis in adults with inadequate response to methotrexate, as monotherapy or with MTX/other nonbiologic DMARDs.
Synonyms: Tofacitinib citrate;540737-29-9;Tasocitinib citrate;Xeljanz;CP-690550 citrate;Xeljanz Xr;Tasocitinib monocitrate;CP-690550-10;CP-690,550-10;O1FF4DIV0D;Tofacitinib monocitrate;CHEBI:71197;DTXSID80202404;RefChem:56139;DTXCID40124895

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EINECS:638-826-4
Molecular formula:C16H20N6O•C6H8O7

Molecular Weight: 504.5
Molecular Formula: C22H28N6O8
Canonical SMILES: CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
InChI: InChI=1S/C16H20N6O.C6H8O7/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16;7-3(8)1-6(13,5(11)12)2-4(9)10/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t11-,13+;/m1./s1
InChIKey: SYIKUFDOYJFGBQ-YLAFAASESA-N
Melting Point: 198-202 °C (dec.)
Purity: 98%
Solubility: In Vitro:
DMSO : ≥ 122.5 mg/mL (242.82 mM)
H2O : 5 mg/mL (9.91 mM; Need ultrasonic and warming)
Application: Janus Kinase Inhibitors
Storage: RT
Synonyms: CP-690550; CP 690550; CP690550; Tofacitinib; tasocitinib.
Description
Tofacitinib (trade name Xeljanz, formerly tasocitinib, CP-690550) is a drug discovered and developed by Pfizer. It is currently approved for the treatment of rheumatoid arthritis (RA) in the United States and is being studied for treatment of psoriasis, inflammatory bowel disease, and other immunological diseases, as well as for the prevention of organ transplant rejection. (source: http://en.wikipedia.org/wiki/Tofacitinib).


More details are to be found on supplier website