Molecular Weight: 494.52
Molecular Formula: C20H22N4O5.CH4O3S
Canonical SMILES: O=C(OCC(N(C)C)=O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O
InChI: 1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22;1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23);1H3,(H,2,3,4)
InChIKey: FSEKIHNIDBATFG-UHFFFAOYSA-N
Boiling Point: 634.6°C at 760 mmHg
Melting Point: 162-164°C
Purity: >98%
Solubility: In Vitro:
DMSO : 125 mg/mL(252.77 mM;Need ultrasonic)
H2O : ≥ 50 mg/mL(101.11 mM)
In Vivo:
1.Add each solvent one by one:PBS
Solubility: 12.5 mg/mL (25.28 mM); Clear solution; Need ultrasonic
2.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline
Solubility: ≥ 2.08 mg/mL (4.21 mM); Clear solution
3.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline)
Solubility: ≥ 2.08 mg/mL (4.21 mM); Clear solution
4.Add each solvent one by one:10% DMSO >> 90%corn oil
Solubility: ≥ 2.08 mg/mL (4.21 mM); Clear solution
Application: Trypsin Inhibitors
Storage: 4°C, sealed storage, away from moisture
* In solvent :
-80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture)
Synonyms: 4-(2-(2-(dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate methanesulfonate; Camostat Mesilate; Camostat Mesylate; FOY 305; FOY-305; FOY305
DescriptionCamostat (INN) or FOY-305 is a serine protease inhibitor. Serine protease enzymes have a variety of functions in the body, and so camostat has a diverse range of uses. It is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or kidney disease orpancreatitis.
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