Description:
E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain.
- Molecular Weight: 357.41
- Molecular Formula: C15H27N5O5
Purity: ≥99% by HPLC
Canonical SMILES:
CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O
InChI:
InChI=1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10-,11-/m0/s1
InChIKey: LTLYEAJONXGNFG-DCAQKATOSA-N
- Solubility: Soluble in DMSO (25 mg/mL), Water (20 mg/mL)
- Appearance: White Crystalline Powder
- Application: For research used only
- Storage: Store at -20°C
Synonyms:
L-trans-Epoxysuccinyl-Leu-4-guanidinobutylamide; Proteinase inhibitor E 64; 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-(2S,3S)-oxiranecarboxylic acid; Thiol protease inhibitor; trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane; 2-Oxiranecarboxylic acid, 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-, (2S,3S)-; L-Trans-Epoxysuccinyl-Leu-agmatine
More details are to be found on supplier website
