Molecular Weight: 212.23
Molecular Formula: C8H8N2O3S
Canonical SMILES: C1=CC=C2C(=C1)C(=NO2)CS(=O)(=O)N
InChI: 1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)
InChIKey: UBQNRHZMVUUOMG-UHFFFAOYSA-N
Melting Point: 160-163 °C
Purity: ≥98%
Solubility: Soluble in DMSO
Application: Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potent
Storage: Store at -20 °C
Synonyms: AD-810; AD-810N; AD 810; AD 810N; AD810; AD810N; 1,2-Benzisoxazole-3-methanesulfonamide; 3-(Sulfamoylmethyl)-1,2-benzisoxazole;
DescriptionZonisamide is the first agent of this chemical class to be developed as an antiepileptic drug blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents.
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