Description:
6-Methoxydihydrosanguinarine is an alkaloid isolated from Hylomecon hylomeconoides. 6-Methoxydihydrosanguinarine exhibits anti-inflammatory activity via inhibition of NO and IL-6 expression, and antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA) strains. 6-Methoxydihydrosanguinarine also induces apoptotic cell death in HT29 colon carcinoma cells dose-dependently.
- Molecular Weight: 363.36
- Molecular Formula: C21H17NO5
Purity: ≥95%
Canonical SMILES:
CN1C(C2=C(C=CC3=C2OCO3)C4=C1C5=CC6=C(C=C5C=C4)OCO6)OC
InChI:
InChI=1S/C21H17NO5/c1-22-19-13(4-3-11-7-16-17(8-14(11)19)26-9-25-16)12-5-6-15-20(27-10-24-15)18(12)21(22)23-2/h3-8,21H,9-10H2,1-2H3
InChIKey: MHPDDMNAUJQRSW-UHFFFAOYSA-N
- Boiling Point: 556.7±50.0°C at 760 mmHg
- Solubility: Soluble in Acetone, Chloroform, Dichloromethane, DMSO, Ethyl Acetate
- Appearance: Powder
- Storage: Store at -20°C
Synonyms:
[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine, 13,14-dihydro-14-methoxy-13-methyl-, (-)-; (-)-13,14-Dihydro-14-methoxy-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine; (-)-Sanguinarine pseudomethanolate; (-)-6-Methoxydihydrosanguinarine
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