CAS No. 835616-60-9

Molecular Formula: C13H9FN2O4

Molecular Weight: 276.22
Molecular Formula: C13H9FN2O4
Canonical SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)F
InChI: InChI=1S/C13H9FN2O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5H2,(H,15,17,18)
InChIKey: CRAUTELYXAAAPW-UHFFFAOYSA-N
Boiling Point: 520.9±45.0 °C (Predicted)
Melting Point: 254-256 °C
Purity: ≥ 98%
Solubility: Slightly soluble in Dichloromethane (Heated), DMSO
Storage: -20 °C
Synonyms: E3 ligase Ligand 4; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-; Thalidomide 4-fluoride; Thalidomide fluoride; 4-Fluoro-thalidomide; Cereblon ligand 4;E3 ligase Ligand 4; 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione
Description
TC-E3 5032 is a linker used in PROTAC technology that can be used in the synthesis of HDAC6 and anaplastic lymphoma kinase (ALK) degraders.


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Assay	99% min
Appearance	white powder
It is an intermediate for the synthesis of N-[2-aminoethyl] Pomalomide TFA salt. N-[2-Aminoethyl] Pomalidomide TFA is a thalidomide derivative, an effective inhibitor of TN Chemicalbook F-α , and an anti-inflammatory and anti-tumor drug for the treatment of multiple myeloma.
Use A ligand for E3 ubiquitin ligase used in PROTAC technology.