Molecular Weight: 348.37
Molecular Formula: C21H17FN2O2
Canonical SMILES: CC1=C(C2=C(N1CC(=O)O)C=CC(=C2)F)CC3=NC4=CC=CC=C4C=C3
InChI: InChI=1S/C21H17FN2O2/c1-13-17(11-16-8-6-14-4-2-3-5-19(14)23-16)18-10-15(22)7-9-20(18)24(13)12-21(25)26/h2-10H,11-12H2,1H3,(H,25,26)
InChIKey: FATGTHLOZSXOBC-UHFFFAOYSA-N
Synonyms: OC-000459; OC 000459; OC000459; 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid
DescriptionTimapiprant is a potent and selective D prostanoid receptor 2 (DP2; CRTH2) antagonist. It effectively improves lung function and symptoms in patients with atopic eosinophilic asthma. It was shown to reduce both nasal and eye symptoms in allergic subjects exposed to grass pollen.
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