Molecular Weight: 388.555
Molecular Formula: C26H32N2O
Canonical SMILES: CC12CCC(CC1=CCC3C2CCC4(C3CC=C4N5C=NC6=CC=CC=C65)C)O
InChI: InChI=1S/C26H32N2O/c1-25-13-11-18(29)15-17(25)7-8-19-20-9-10-24(26(20,2)14-12-21(19)25)28-16-27-22-5-3-4-6-23(22)28/h3-7,10,16,18-21,29H,8-9,11-15H2,1-2H3/t18-,19-,20-,21-,25-,26-/m0/s1
InChIKey: PAFKTGFSEFKSQG-PAASFTFBSA-N
Purity: >98%
Synonyms: TOK-001; TOK 001; TOK001; NX41765; NX 41765; NX-41765; VN 124; VN124; VN-124; VN/124-1; (3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol
DescriptionGaleterone (TOK-001 or VN/124-1) is a novel antiandrogen under development by Tokai Pharmaceuticals for the treatment of prostate cancer. It possesses a unique dual mechanism of action, acting as both anandrogen receptor antagonist and an inhibitor of CYP17A1, an enzyme required for the biosynthesis of theandrogens.
More details are to be found on
supplier website
![Chemical-Suppliers](../images/Frot_10.gif")
